The Quantum Nanoscience Laboratory at the University of Sydney offers extensive measurement capability combining ultra-low temperatures (three dilution fridges with based temperatures below 10 millikelvin) with a suite of radio and microwave frequency electronics and test equipment. Our research is exploring many of the engineering challenges for reading out and controlling qubits in scaled-up architectures. In addition, we are developing specialised instrumentation and tools needed to undertake the next generation of quantum experiments, such as high-speed cryogenic electronics. The facilities at Sydney include purpose built laboratories and cleanrooms for nanofabrication and quantum science. These facilities enable a range of nanoscale quantum systems to be investigated at low temperature, high magnetic field and on short timescales - where exotic quantum phenomena become apparent.